The EU has proven how tough it can be in enforcing its antitrust laws.
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So no matter how tough things get, this is not a country that quits.
Can you imagine how tough that would be and how scared they might be?
And I remember traveling here right after they happened and how tough things were.
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But no matter how tough you are, there are times when the strain takes its toll.
There have been signs of differences in the Bush administration over how tough a stance to take.
But at this stage we know how tough it will be to qualify.
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But no matter how tough the situation gets for pharmaceutical industry, Dora will not be leaving any stone unturned.
The following CEO dilemma captures the truth of how tough business will continue to be during the Turbulent 2000s.
Michelle and I remember how tough it can be to find good childcare.
And I know how tough times are -- in Los Angeles, in California, but also all across the country.
But I'm realistic, because I understand how tough it is inside of Iraq.
You know with the economy, and the foreclosures on homes, and how tough it is to make it with families.
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The critics never understand how tough it is in the corner office being a CEO is this day and age.
Koner attributes the outpouring of generosity to a heightened awareness for how tough times present a new outlook on giving.
"No matter how tough you are, how much bravado you have, you are going to miss international rugby, " he said.
Brewer acknowledged that he wonders how tough the Knicks would be defensively if he and Shumpert played on the wings.
We have all seen on TV how tough, and dangerous, fishing for Alaskan crab is, or the dangers of logging.
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The young Marines know exactly how tough the fight they are facing in the coming weeks and months will likely be.
I'd almost forgotten how tough it is to live in New Orleans.
But we have seen how tough it is to adjust entitlement programs.
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And we will be able to feel good about ourselves and sanctimonious about how pure our intentions are and how tough we are.
"I must stress how tough it is to meet these targets with the cuts we are getting from the UK government, " said Mrs Hutt.
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Shareholders and boards themselves are starting to realize just how tough it is to do this job, as compensation committees are generally getting poor marks.
How tough was it for recent grads to find a job?
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That gives you some sense of how tough the politics are.
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Looking at taxes and spending as a share of GDP shows just how tough it will be for the parties to reach a fiscal compromise.
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The pro-biotech Mr Rodrigues, himself a farmer, is tussling with his cautious colleague, Marina Silva, the environment minister, over how tough the procedure should be.
He told me the sequester is going to go through, at least for a few days, because both sides need to prove how tough they are.
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