癌基因,肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
目的:比较B,C两种基因型HBV核心蛋白在促进肝细胞凋亡方面的差异,以期初步阐述HBV基因型与临床关系的发病机制。
AIM: To compare the proapoptosis effect of hepatitis B virus (HBV) genotype B and C core proteins on liver cells, and explore the pathogenesis of HBV infection with different genotypes.
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖;
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
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