癌基因，肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
目的：比较B，C两种基因型HBV核心蛋白在促进肝细胞凋亡方面的差异，以期初步阐述HBV基因型与临床关系的发病机制。
AIM: To compare the proapoptosis effect of hepatitis B virus (HBV) genotype B and C core proteins on liver cells, and explore the pathogenesis of HBV infection with different genotypes.
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖；
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
结论胰腺癌细胞中缺失PUMA基因表达，PUMA转染胰腺癌细胞后表达PUMA，并能促进细胞凋亡。
Conclusions Re-expression of PUMA gene, the expression of which is lost in human pancreatic adenocarcinoma, induces apoptosis, thus inhibiting tumor growth.
设计合适的核酶分子能够阻断癌基因的异常表达，逆转肿瘤细胞MDR，促进肿瘤细胞凋亡，有望成为肿瘤基因治疗的有效手段之一。
With appropriate designing, it could block oncogene's expression, reverse MDR, and promote tumor cell apoptosis. All these properties make the Ribozymes as potentially useful regent for gene therapy.
中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression.
中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression.
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