跟一个愿意真正倾听并不会置你的感受于不顾的朋友谈谈。

Talk to a friend who will really listen and not brush aside your feelings.

《柯林斯英汉双解大词典》

她不顾父母的强烈反对，决定去上夜校。

She decided to go to the evening school regardless of her parents' strong objection.

youdao

但是如果有些药物拥有着这样的可能性，它能明显改善那些无法治愈的病人生命状况的话，我们将会迎难而上，毫不顾及市场规模的问题。

But if we have a possibility to significantly improve the lives of patients who cannot be well treated, we'll go ahead, irrespective of the size of the market.

youdao

He went, the news account tells us, rather against the advice of his friends.

据报道，他不顾朋友的反对。

耶鲁公开课 - 公正课程节选

By now the cabin boy, Parker, is lying at the bottom of the lifeboat in the corner because he had drunk seawater against the advice of the others and he had become ill and he appeared to be dying.

现在派克正蜷缩在救生艇的角落,因为他不顾众人劝阻饮用了海水,他生病了，而且似乎快死了。

耶鲁公开课 - 公正课程节选

Milton's constructing -- it's a remarkable and impossible strategy here, and it's one we can call a strategy of retrospective anticipation Of course, this retrospective anticipation can only be a fiction.

弥尔顿用了--这种手法很奇妙而且不可能，我们可以称之为返顾预测的手法,这是一种。。。，当然，，and，it’s，a，type，of…,返顾预测是不可能的。

耶鲁公开课 - 弥尔顿课程节选