Researchers at Duke University scrutinized more than 160 published studies and found an absence of strong evidence that any of these approaches can make a big difference.
杜克大学的研究人员详细核查了160多项已发表的研究，发现并没有强有力的证据表明这些方法中的任意之一能产生重大作用。
A little effort every day, you will make a big difference.
每天付出一点努力，你就会有很大的不同。
When it comes to climate change, can they make a big difference?
在气候变化问题上，他们能起到很大的作用吗？
She believed that such an experience would make a big difference to her 9-year-old boy's life.
她相信这样的一次经历会给9岁孩子的人生带来很大的改变。
That one little change can make a big difference in the overall look of your shot.
这一点小小的改变会给照片的整体效果带来非常大的改变。
For such smaller Banks, even modest inflows of new deposits can make a big difference.
对于这些小银行来说，即使小的新的资金流入也能够产生大的作用。
Veganism might not be popular, but it can make a big difference to CO2 and methane emissions.
纯素食主义可能并不受欢迎，但对于二氧化碳和甲烷排放来说，它的减排作用非常大。
Making a few simple changes, a few different choices can make a big difference in the long run.
从长远来看，做出一些简单的改变和一些不同的选择就可以产生很大的影响。
Sometimes having an experienced coach there who has seen it all before can make a big difference.
有时拥有一个阅历丰富的教练会产生很大不同。
Sometimes, making a shift like waking earlier or changing a daily routine can make a big difference.
有时，做一些诸如早起或改变一下日常作息等的小调整就可以带来巨大的改变。
Getting your swap space configuration right can make a big difference to the efficiency of your machine.
正确配置交换空间可以对计算机效率产生巨大的影响。
And when we do that, we are going to really make a big difference in helping elevate the age of participation for women.
我们如果这样做，就确实能为帮助推动妇女参与的时代作出重大贡献。
And the choices you make, throughout your careers, through the next 50 years of your life, can make a big difference as well.
你们所作的选择，在你们的整个生涯中，在你们未来50年的生活中，也能够产生很大的影响。
Right communications technology really can make a big difference in the success of organizations, especially small businesses.
而且交流技术也的确对组织的成功产生重大影响，尤其是小公司。
While we're on the topic of little software features that can make a big difference, I want the ability to set an icon for a folder.
现在我们来谈论一个小的但能产生大的区别的软件功能项，我希望有给文件夹设定图标的能力。
About 45, 000 women are diagnosed with breast cancer every year in the UK, so it is clear these changes could make a big difference.
英国每年有约45000名女性确诊为乳腺癌患者，因此，显然这些生活方式的改变会大有裨益。
And the right communications technology really can make a big difference in the success of organizations, especially small businesses.
而且交流技术也的确对组织的成功产生重大影响，尤其是小公司。
Even on a single CPU machine this will make a big difference, as you do not waste as much time waiting on a response from a Web service.
即使是在一个单CPU 的计算机上，多线程也会带来很大的不同，因为您不必花费大量时间等待Web服务的响应。
While it's hard for many people to control their diet like that, many doctors are saying that even small steps can make a big difference.
虽然对很多人来说，要像那样控制饮食很困难，但许多医生都说，即使是小小的一步也可以造成很大的不同。
Signs of ASDs can usually be seen in infants and toddlers, and early intervention therapies can make a big difference in a child's development.
ASD症状常见于婴幼儿群体，所以早期干预治疗对儿童的发育往往起到至关重要的作用。
But not always, because the order of the columns in the index can make a big difference depending on the query. For example, consider this query.
但也不一定，因为索引中列的顺序也许会根据查询而有很大差异。
But in otherwise normal children, the environment in which they are reared can make a big difference in whether empathy is fostered or suppressed.
但是对其它正常的孩子来说，他们的同情心是被引导还是被抑制，成长环境起着相当大的作用。
Marie Hunt of CB Richard Ellis (CBRE), a property consultancy, points out that in such places even an oversupply of 20 homes can make a big difference.
地产咨询公司世邦魏理仕（CBRichardEllis）的玛丽•亨特（Marie Hunt）指出，在这些地区，20套房子的超额供给就会造成极大的区别。
Research over the past 20 years have pointed to the importance of micronutrients - substances found in small amounts in foods that make a big difference.
过去20多年的研究已经指出微量营养素的重要性—食物中发现的极少量的物质起着很大的作用。
Ncell says its new network will also make a big difference to mountaineers, who can now receive weather reports and safety information while they’re climbing.
Ncell表示新的网络将给登山者带来巨大的改变，在攀登的过程中他们就可以收到天气安全方面的信息。
If a headset isn’t feasible, holding your phone just slightly away from your ear can make a big difference; the intensity of radiation diminishes sharply with distance.
如果你连蓝牙无线耳麦也没有的话，将电话拿离耳朵稍微远一点，也会有很大的不同，辐射的强度会随着距离的拉远而迅速减少。
But there are a few variables that can be controlled, and they can make a big difference in how valuable you are as an employee: Dedication, visibility, and special skills.
可是有一些可变因素是可以控制的，而它们在对你作为员工来说价值多少会发挥很大影响：敬业、可视性和特殊技能。
And although you did not get everything you wanted, you have acquired enough of a budget to make a big difference in the security and reliability of the overall architecture.
尽管并没有获得想要的所有东西，但已经获得了足够的预算，可以满足极大改善总体体系结构的安全性和可靠性的需求。
I don't know that I make a big difference in the lives of the kids that I work with, but I do know that I can take some pressure off of those that are able to devote more time.
我不知道我给我帮助的孩子们的生活带来了很大的变化，但是我知道我可以舒缓一些能够献出更多时间的人的压力。
I don't know that I make a big difference in the lives of the kids that I work with, but I do know that I can take some pressure off of those that are able to devote more time.
我不知道我给我帮助的孩子们的生活带来了很大的变化，但是我知道我可以舒缓一些能够献出更多时间的人的压力。
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