They are set to make a big fat profit.
他们决心努力大赚一笔。
School fees can make a big hole in your savings.
学费可以花掉一大笔储蓄。
The Joneses make a big deal out of being "different."
琼斯一家子把“与众不同”看作是了不得的事。
She doesn't want to make a big emotional commitment to Steve at the moment.
她不想在此刻对史蒂夫在感情上作出重大的承诺。
Your choice of words can make a big difference, too.
你的用词也会产生很大的影响。
Inventions usually make a big difference to people's lives.
发明通常对人们的生活有很大的影响。
For small mammals, microclimates can make a big difference.
对于小型哺乳动物来说，微气候可以产生很大的影响。
This little bit of support can sometimes make a big difference.
这种小小的支持有时会产生很大的影响。
Even a few hours a month can make a big difference in someone's life.
即使是一个月几个小时，也会对一个人的生活产生很大的影响。
That would make a big difference.
那就将使情况大为改观了。
This can make a big difference to local prices.
这可以使它获得与当地的悬殊价差。
Paging space can make a big demand on disk space.
分页空间可能需要大量磁盘空间。
What happens when you need to make a big decision?
当你需要做出重大决定时会怎样？
He could make a big acquisition or buy back shares.
他可能会进行大额并购或者回购股票。
Even relatively mild stresses make a big difference.
即使相对柔和的压力也会带来很大改变。
Sometimes the simplest gesture can make a big statement.
有时候最简单的举动也非同凡响。
Say, you know what I want to make a big stink about now?
You want to make a big stink ？有什么事让你不满意呀？
This small change in your mindset can make a big difference.
头脑中这一点小小的变化将会很大改变。
A few years can make a big difference in the life of a nation.
在一个民族的历史长河中，短短几年的时间就有可能被改变一切。
But whether or not you do so doesn't seem to make a big difference.
但不论你是否选择这样做，都不会有什么太大的影响？
It's human nature. There's no need to make a big fuss about it.
这是人类本性，没有必要小题大做。
Whenever he comes, I make a big production of finding my wallet.
无论他什么时候过来，我总是要大张旗鼓地找一回钱包。
I'm sure it would make a big difference to our learning ability.
我相信这一改变能够大大提高我们的学习能力。
'Transparency is going to make a big difference,' the aide said.
这位助手说，透明将带来很大的转变。
But I am confident that improving diet can make a big difference.
但是我坚信着改善饮食习惯是可以改变这种状况的。
Is it a goal that will really make a big difference in your life?
有没有什么目标会真正的让你的生活不一样的呢？
To make a big impression, consider these outrageous romance tips.
为了给恋人留下深刻的印象，你可以考虑采用这些粗犷型的浪漫技巧。
To make a big impression, consider these outrageous romance tips.
为了给恋人留下深刻的印象，你可以考虑采用这些粗犷型的浪漫技巧。
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