Without a doubt, each of the small decisions you make in this realm can make a big impact on your health in the years to come.

毫无疑问，你在这方面做出的每一个小决定都会在未来几年对你的健康产生重大影响。

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The Joneses make a big deal out of being "different."

琼斯一家子把“与众不同”看作是了不得的事。

《柯林斯英汉双解大词典》

She doesn't want to make a big emotional commitment to Steve at the moment.

她不想在此刻对史蒂夫在感情上作出重大的承诺。

《牛津词典》

A few degrees can make a big difference when it comes to food storage.

VOA: special.2009.02.09

And we're data junkies, so we like to get a lot of data before we make a big decision like that.

我们是数据控，所以一般先收集很多数据,在做重大决定的时候。

斯坦福公开课 - 戴尔CEO-Michael.Dell谈创业和发展课程节选

So we make a big minor map which they help to paint.

因此我们在孩子们的帮助下,绘制了一幅小型地图。

麻省理工公开课 - 媒体、教育、市场课程节选

But if you are designing a collaborative session, it can make a big difference.

FORBES: Want Collaboration? Watch Where You Sit.

And I think those who dismiss that out of hand make a big mistake.

FORBES: Get Ready For The Skeet Shooting Truthers!

And that decision can make a big difference in the eventual size of your nest egg.

FORBES: Back To The Future: Rethinking Retirement