Without a doubt, each of the small decisions you make in this realm can make a big impact on your health in the years to come.
毫无疑问，你在这方面做出的每一个小决定都会在未来几年对你的健康产生重大影响。
它们可能会制造很大的噪音。
A little effort every day, you will make a big difference.
每天付出一点努力，你就会有很大的不同。
When it comes to climate change, can they make a big difference?
在气候变化问题上，他们能起到很大的作用吗？
She believed that such an experience would make a big difference to her 9-year-old boy's life.
她相信这样的一次经历会给9岁孩子的人生带来很大的改变。
Most adults, when they fall down, make a big deal out of it and don't even make a second attempt.
大多数成年人，当他们摔倒了，会对此大惊小怪，甚至不会再试一次。
Children can be careless about things like that, and he won't make a big fuss about it unless it becomes a regular thing.
孩子们在这种事情上可能会粗心大意，但除非这成为常态，否则他不会大惊小怪。
While that helped make a big improvement in my mental health, the biggest reason for it was truly communicating with people.
虽然这大大改善了我的心理健康，但最大的原因是真正与人交流。
Researchers at Duke University scrutinized more than 160 published studies and found an absence of strong evidence that any of these approaches can make a big difference.
杜克大学的研究人员详细核查了160多项已发表的研究，发现并没有强有力的证据表明这些方法中的任意之一能产生重大作用。
I'd rather not make a big career change now. I like what I'm doing.
我现在不愿意在事业上有太大的变动，我挺喜欢现在的职业。
My greatest fear is to make a big mistake-not to predict an eruption.
我并不害怕预测火山何时喷发，我只是担心自己会酿成大错。
At first, my kids would make a big deal when I left the house to run.
最初的时候，当我从家里开始往外跑步的时候，我的小孩还跟我打赌。
For most people, the smart way to buy a home is to make a big down payment.
对于大多数人来说，聪明的办法是购房时首期付款尽可能多支付。
That one little change can make a big difference in the overall look of your shot.
这一点小小的改变会给照片的整体效果带来非常大的改变。
Chase: you don't have to make a big deal about it, I just thoughtI'd let you know.
切斯：你别把这当什么大事儿，我就想让你知道我的心意罢了。以后我决定每周二都过来说一下咯。
Fear of rejection is probably one reason people make a big effort not to fail at work.
对排斥的恐惧可能是一个人们尽最大努力不在工作上失败的原因。
For such smaller Banks, even modest inflows of new deposits can make a big difference.
对于这些小银行来说，即使小的新的资金流入也能够产生大的作用。
You can visit clients and make a big impression just by giving them some hands-on help.
你可以拜访一些客户，给予他们一些实际的帮助，这会给他们留下深刻的印象。
I usually make a big deal about content preceding design, and presentations are no exception.
通常，我会在设计内容导入上下很大功夫，做报告时也是如此。
Making a few simple changes, a few different choices can make a big difference in the long run.
从长远来看，做出一些简单的改变和一些不同的选择就可以产生很大的影响。
Sometimes having an experienced coach there who has seen it all before can make a big difference.
有时拥有一个阅历丰富的教练会产生很大不同。
As children grow older than my patient, behavioral and other treatments can make a big difference.
当孩子长大到一定年龄之后，症状和治疗方式都会有很大的不同。
Afterward, all I wanted to do was to make a big salad, and that’s exactly what I did, sans TV shows.
之后，我原来只想做的就是一大份沙拉——我的确做了——同时不看电视节目。
Sometimes, making a shift like waking earlier or changing a daily routine can make a big difference.
有时，做一些诸如早起或改变一下日常作息等的小调整就可以带来巨大的改变。
That information can make a big difference in the campaigns and offers made to members of such a household.
由此获得的讯息可以极大地区分这样一个家庭中成员的活动和出价的不同。
The problem with this is that higher spending and tax cuts will only make a big budget deficit even bigger.
此举带来的问题便是增加支出和削减税收，而这只会使本处高位的财政赤字更加高而已。
Often a very simple change, like changing the GC policy that your app USES, can make a big improvement.
通常，非常简单的更改(如更改应用程序使用的GC策略)会产生非常大的改进。
Often a very simple change, like changing the GC policy that your app USES, can make a big improvement.
通常，非常简单的更改(如更改应用程序使用的GC策略)会产生非常大的改进。
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