An example is production of certain molecules called cytokines by T-cells that activate themselves.
细胞能分泌这类叫做细胞因子的分子,实现自激活
Now, t-cells are also involved in humoral immunity but they're not the end result.
细胞也参与体液免疫,但它并不是体液免疫的最终应答结果
Now that's going to be important when we talk about making human gene - making human proteins inside alternate hosts like bacteria, that they can't do all the things that your cells can do.
这一步骤在我们谈到,利用像细菌那样的宿主,来生成人类蛋白时非常重要,因为细菌并不具备人类细胞的全部功能
When these CD8 T-cells see your MHC1 together with an antigen that doesn't belong in you, it creates an immune response.
当CD8 T细胞识别MHC1时,同时识别了不属于你的抗原,由此产生免疫反应
So, the classes of T-cells: macrophages, natural killer cells, these are a class of cells that's particularly important called dendritic cells.
这类T淋巴细胞包括巨噬细胞,自然杀伤细胞等 统称为树突细胞,树突细胞尤为重要
The main effector cells in cell mediated immunity, the cells that do the main business are called T-cells.
细胞免疫中的主要效应细胞,即发挥主要作用的细胞是T细胞
Helper cells don't become cytotoxic cells but they help B cells become antigen producing - antibody producing cells.
附助细胞不会成为细胞毒细胞,它们帮助B细胞成为抗体分泌细胞
The antigen has to be presented to helper T-cells, those helper T-cells have to stimulate a B-cell population to both proliferate and differentiate.
抗原需要被呈递给辅助性T细胞,这些辅助性T细胞需要激活B淋巴细胞,使其增殖和分化
The immune system, some cells of the immune system, in particular this class of T-cells called CD8 cells have receptors which recognize MHC1.
免疫系统,其中一些免疫细胞,特别是T细胞中的,CD8细胞含有可识别MHC1的受体
So, that's antigen presentation to this population of cells called cytotoxic T-cells, Tc, a subset of the class of T-cells in the immune system.
这些细胞被呈递给另一种细胞,这些细胞被称为细胞毒性T细胞,是免疫系统中T淋巴细胞的亚群中的一种
Another subset of T-cells called T helper cells will recognize that signal by direct contact with it, and they will become activated and proliferate.
另外一个T细胞的亚群是辅助性T细胞,辅助性T细胞可识别与其接触的抗原信号,并被激活,开始增殖
In this case here, you're generating host cells, cytotoxic T-cells, that can kill only very specific cells, cells that are expressing this foreign antigen.
而在这个例子中,人产生宿主细胞,即细胞毒性T细胞,它只会消灭特定的细胞,也就是携带特定异己抗原的细胞
Because it has MHC-1, your MHC-1 on it, this T-cell recognizes that it's one of your cells but it has a foreign antigen associated with it.
因为该细胞上有MHC-1,T细胞将这些细胞识别为自身细胞,但这些细胞带有异己抗原
Here's where the intelligence of the immune system comes in, is that these cytotoxic T-cells that are generated only kill cells that have this signal on it.
免疫系统的聪明之处就在此,这些细胞毒T细胞,只能杀死具有特殊标记信号的细胞
They become activated and they produce, eventually, mature cytotoxic T-cells in large numbers.
细胞毒性T细胞活化后,开始增殖,最终,产生大量成熟的细胞毒性T细胞
Now, these Th-cells, helper T-cells, go on to stimulate B-cells, and it's these B-cells that become the mature antibody producing cells that make quantities of antibody that fill up in your body.
这些辅助性T细胞,进一步刺激B淋巴细胞,从而使这些B淋巴细胞,逐渐发育成成熟的抗体生成细胞,可在体内产生大量抗体
So, either stimulates the production of-- and differentiation of B-cells, to produce a specific antibody that can neutralize the virus, or stimulates the production of cytotoxic T-cells that can kill infected cells within your body.
所以,疫苗的刺激要么能够,促进B淋巴细胞产生和分化,以生成特定的抗体来杀灭病毒,要么刺激T细胞释放细胞毒素,杀死身体里被感染的细胞
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