In an accompanying editorial, Edward Livingston of the University of Texas says the relatively small influence of volume on success of the transplants raises a big question.

VOA: standard.2010.07.14

But finally, Reiner says, well, thank you for visiting us, it's all very wonderful, but you know our audience would really like to know; it seems like a simple question but it's awfully hard to understand, but how can a great, big, enormous, heavy thing like this airplane get off the ground?

但最后 雷纳说到,谢谢你的来访,太棒了,但你知道吗,我们的观众非常想知道,这问题貌似简单,但却很难让人明白,问题是,像这么一个巨大且沉重的飞机,是如何飞起来的呢

耶鲁公开课 - 古希腊历史简介课程节选

Transparency remains a big question in Gabon.

VOA: standard.2009.08.28

"So there's a big question mark,". "Who is responsible for such a heavy increase of production and export of the narcotics, because all of the areas where this cultivation is underway are controlled by NATO forces in one way or other?" Akhonzadeh said this reality cannot be ignored and called for new ideas,strategies and methods to tackle the problems of Afghanistan.

VOA: standard.2009.03.27