Without a doubt, each of the small decisions you make in this realm can make a big impact on your health in the years to come.
毫无疑问，你在这方面做出的每一个小决定都会在未来几年对你的健康产生重大影响。
They are set to make a big fat profit.
他们决心努力大赚一笔。
School fees can make a big hole in your savings.
学费可以花掉一大笔储蓄。
The Joneses make a big deal out of being "different."
琼斯一家子把“与众不同”看作是了不得的事。
She doesn't want to make a big emotional commitment to Steve at the moment.
她不想在此刻对史蒂夫在感情上作出重大的承诺。
它们可能会制造很大的噪音。
Your choice of words can make a big difference, too.
你的用词也会产生很大的影响。
A little effort every day, you will make a big difference.
每天付出一点努力，你就会有很大的不同。
For small mammals, microclimates can make a big difference.
对于小型哺乳动物来说，微气候可以产生很大的影响。
Inventions usually make a big difference to people's lives.
发明通常对人们的生活有很大的影响。
This little bit of support can sometimes make a big difference.
这种小小的支持有时会产生很大的影响。
When it comes to climate change, can they make a big difference?
在气候变化问题上，他们能起到很大的作用吗？
Even a few hours a month can make a big difference in someone's life.
即使是一个月几个小时，也会对一个人的生活产生很大的影响。
She believed that such an experience would make a big difference to her 9-year-old boy's life.
她相信这样的一次经历会给9岁孩子的人生带来很大的改变。
Most adults, when they fall down, make a big deal out of it and don't even make a second attempt.
大多数成年人，当他们摔倒了，会对此大惊小怪，甚至不会再试一次。
Children can be careless about things like that, and he won't make a big fuss about it unless it becomes a regular thing.
孩子们在这种事情上可能会粗心大意，但除非这成为常态，否则他不会大惊小怪。
While that helped make a big improvement in my mental health, the biggest reason for it was truly communicating with people.
虽然这大大改善了我的心理健康，但最大的原因是真正与人交流。
Researchers at Duke University scrutinized more than 160 published studies and found an absence of strong evidence that any of these approaches can make a big difference.
杜克大学的研究人员详细核查了160多项已发表的研究，发现并没有强有力的证据表明这些方法中的任意之一能产生重大作用。
That would make a big difference.
那就将使情况大为改观了。
This can make a big difference to local prices.
这可以使它获得与当地的悬殊价差。
Paging space can make a big demand on disk space.
分页空间可能需要大量磁盘空间。
What happens when you need to make a big decision?
当你需要做出重大决定时会怎样？
He could make a big acquisition or buy back shares.
他可能会进行大额并购或者回购股票。
Even relatively mild stresses make a big difference.
即使相对柔和的压力也会带来很大改变。
Sometimes the simplest gesture can make a big statement.
有时候最简单的举动也非同凡响。
This small change in your mindset can make a big difference.
头脑中这一点小小的变化将会很大改变。
A few years can make a big difference in the life of a nation.
在一个民族的历史长河中，短短几年的时间就有可能被改变一切。
A few years can make a big difference in the life of a nation.
在一个民族的历史长河中，短短几年的时间就有可能被改变一切。
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