HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
在正常生长条件下,热激因子处于钝化的单体状态,而当热激时,热激因子形成三聚体并与DNA结合,同时通过转录激活域的活化而激活热激基因的表达。
The invention includes antibodies that provide superior anti-coagulant activity by binding native human TF with high affinity and specificity.
本发明包括抗体,该抗体通过以高度亲和力及特异性结合天然人类TF而提供优异抗凝血活性。
After dissolution of inclusion bodies in binding buffer containing 8m Urea, the fusion protein was purified with metal affinity chromatography column, high purity protein was achieved.
包涵体蛋白经含8m尿素的结合缓冲液溶解后,用金属亲和层析法进行纯化,获得了高纯度的目的蛋白。
The compounds show a high and selective binding affinity for the histamine H3 receptor, indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity.
这些化合物表现出对组胺h 3受体的高度和选择性亲和力,从而表现出组胺h3受体的拮抗、反激动剂或激动剂活性。
The compounds show a high and selective binding affinity for the histamine H3 receptor, indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity.
这些化合物表现出对组胺h 3受体的高度和选择性亲和力,从而表现出组胺h3受体的拮抗、反激动剂或激动剂活性。
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