请设计一个实验研究受体与配体结合的特异性 高亲和力 ( high affinity binding ) 受体与配体结合的能力称为亲和力。通过配体与受体结合反应的动力学分析可获得亲和力的信息。
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HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
在正常生长条件下，热激因子处于钝化的单体状态，而当热激时，热激因子形成三聚体并与DNA结合，同时通过转录激活域的活化而激活热激基因的表达。
The invention includes antibodies that provide superior anti-coagulant activity by binding native human TF with high affinity and specificity.
本发明包括抗体，该抗体通过以高度亲和力及特异性结合天然人类TF而提供优异抗凝血活性。
The compounds show a high and selective binding affinity for the histamine H3 receptor, indicating histamine H3 receptor antagonistic, inverse agonistic or agonistic activity.
这些化合物表现出对组胺h 3受体的高度和选择性亲和力，从而表现出组胺h3受体的拮抗、反激动剂或激动剂活性。
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