HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
在正常生长条件下，热激因子处于钝化的单体状态，而当热激时，热激因子形成三聚体并与DNA结合，同时通过转录激活域的活化而激活热激基因的表达。
HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
在正常生长条件下，热激因子处于钝化的单体状态，而当热激时，热激因子形成三聚体并与DNA结合，同时通过转录激活域的活化而激活热激基因的表达。
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