地洛他定为淡蓝色薄膜包衣片，具有长效抗组胺作用，不会阻滞心脏钾通道，从而改善了药物对心血管系统的安全性。本品一日1次，每次5mg。
结论：地洛他定片治疗过敏性鼻炎安全、有效。
Conclusion: Desloratadine in treating allergic rhinitis is effective and safe.
前言：目的：合成地洛他定和n甲酰基地洛他定原料。
Objective: To synthesize desloratadine and its N-formyl derivative.
方法：采用LC/MS/MS（APCI源）测定地洛他定的血浆浓度，并计算药代动力学参数。
METHODS: The concentrations of desloratadine were determined by LC/MS/MS with APCI and the pharmacokinetic parameters were calculated.
应用推荐