长期应用受体拮抗药会发生受体的数量或敏感性增加的现象,称为受体上调(up-regulation);反之,长期应用受体激动药会发生受体的数量减少或敏感性减弱的现象,称为受体下调(down-regulation)。
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相关 研究发现statins 可以向上调控(up-regulation)内皮细胞 NO合成酶(endothelial NO synthase; eNOS)的表现和 活性,改善因缺氧和氧化低密度胆固醇所造成eNOS 向下调控(down-regu...
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up regulation 上调 ; [生理] 增量调节 ; 向上调节
receptor up-regulation 受体向上调节
follow-up regulation system 随机调节系统
homologous up-regulation 同源性上调
up- regulation 向上调节
CRC check-up regulation CRC校验法
There were significant change in cytokines expression in serum and PBMC after treatments(IL-8 down-regulation,p﹤0.01;IL-10、IFN-γ up-regulation,p﹤0.05) .
两种方案治疗后细胞因子的表达较治疗前有明显变化(IL-8下调,P<0.01; IL-10、IFN-γ上调,P<0.05)。
参考来源 - IL·2,447,543篇论文数据,部分数据来源于NoteExpress
During EAE BBB destruction involved many factors and up-regulation expression of ICAM-1 may play an important role.
EAE时BBB破坏的参与因素很多,ICAM一1的上调表达在其中起了重要的作用。
Stimulation of this receptor in vitro results in up-regulation of activated extracellular signal–regulated kinase (ERK).
体外实验中对相应受体进行刺激后导致对细胞外信号调节酶(ERK)的激活有促进作用。
The injury induced by these ventilation strategies includes alterations to the surfactant system and up-regulation of inflammatory markers.
这些通气策略所致的肺损伤包括表面活性物质的改变和炎性标记物的表达上调。
This is something that's very important in the United States because, as I mentioned, insurance regulation is divided up over the fifty states and the problem that that creates is-- it's a nightmare for insurance companies because every different state has different laws.
在美国,这个协会是非常重要的,因为,就像我所提及的,保险监管被分散到了五十个州,这对任何一个保险公司而言,都是一个噩梦,因为各州法律各有不同
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