CTCF的缺失和突变可能导致肿瘤的发生。

Deletion and mutation of CTCF is associated with cancer.

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肿瘤血管生成与肿瘤的发生和转移密切相关。

Tumor angiogenesis plays an important role in tumor growth and metastasis.

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尽管如此，一旦被免疫系统不恰当的控制，EB病毒可以导致肿瘤的发生。

However, when not properly controlled by the immune system, EBV can reactivate causing tumours.

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