PTEN的失活与肿瘤的发生紧密联系。
Furthermore, the inactivation of PTEN is associated with occurrence of tumor.
端粒酶与肿瘤的发生有十分密切的联系。
Tumorigenesis is cogently associated with the activation of telomerase.
CTCF的缺失和突变可能导致肿瘤的发生。
肿瘤血管生成与肿瘤的发生和转移密切相关。
Tumor angiogenesis plays an important role in tumor growth and metastasis.
瘤内新生血管的多少与肿瘤的发生部位及大小有关。
There was a close relationship between the number of developing vessels and the location and size of the tumor.
端粒酶与细胞生长、繁殖、衰老及肿瘤的发生密切相关。
Telomerase is closely related with cell growth, proliferation, senescence and carcinogenesis.
一旦它出现故障就可导致多种人类疾病尤其是肿瘤的发生。
Its malfunction is implicated in various human diseases, especially types of cancer.
肿瘤是一种基因病，基因组的稳定与否和肿瘤的发生密切相关。
Cancer is one of the gene diseases. The genome stability is closely associated with the occurrence of cancers.
新生血管生成在肿瘤的发生和生长过程中是一个至关重要的事件。
Angiogenesis is one of the crucial events for cancer development and growth.
现代医学目前认为肿瘤的发生是由多基因相互协同作用的癌变过程。
Modern medical science recent date consider that the happening of tumor is a cancer progression because a lot of genes work each other in coordination.
COX - 2是环氧化酶的诱导型，参与炎症反应和肿瘤的发生。
COX-2, which is the inducible form, involved in inflammation and cancer incidence.
导致动物多器官肿瘤的发生与丙烯酰胺的代谢产物环氧丙酰胺有关。
The results enunciation:The neurotoxicity probably relates with acrylamide and the animal tumor outcome occurring in some organs probably relates with glycidamide .
热饮热食：热损伤可能是促进肿瘤的发生或成为肿瘤发生的一个条件。
Hot drinks: Heat injury may promote tumor or tumor as a condition.
在人体中，它与色素障碍性疾病及恶性黑色素肿瘤的发生与治疗有关。
In human being, tyrosinase is the key enzyme for melanin biosynthesis, and is associated with melanin hyperpigmentation such as melasma, freckles, ephelide, senile lentigines.
尽管如此，一旦被免疫系统不恰当的控制，EB病毒可以导致肿瘤的发生。
However, when not properly controlled by the immune system, EBV can reactivate causing tumours.
这可能是肿瘤细胞发生免疫逃逸，从而导致肿瘤的发生或者转移的原因之一。
It may be one reason for immune escape of tumor cells that induces the development and metastasis of tumor.
研究者推荐，为预防第二肿瘤的发生，男性乳腺癌患者需要更加严密的监测。
The researchers recommend that men who have suffered from breast cancer need to be more closely monitored for this second onset of cancer.
目的：许多证据表明肿瘤的发生与细胞DNA损伤修复能力下降有密切关系。
Objective: Much evidence show that tumor development is related to the ability of cell 's DNA repair system.
侵袭行为危险程度与胃肠道梭形细胞肿瘤的发生部位相关（P<0·05）。
The risk of invasion behavior was related to the location of these tumors(P<0.05).
DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用。
DNA methylation and its aberrance play an important role in the human development and tumorigenesis.
背景：细胞增殖和凋亡失衡将导致肿瘤的发生，并直接影响肿瘤的生物学行为。
Background: Imbalance of cell proliferation and apoptosis leads to the development of cancers, and may directly in-fluence the biological behaviors of the carcinomas.
据报道，GSTM1、GSTT1基因多态性与多种恶性肿瘤的发生密切相关。
It has been reported that GSTM1, GSTT1 genetic polymorphisms are associated with several malignancies.
结合文献，就XP患者的临床、分型、血缘关系及肿瘤的发生进行了分析讨论。
The clinical features, classification, consanguinity and tumor incidence in XP are discussed.
癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。
Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.
DNA损伤还是突变的重要原因，而严重的突变可造成细胞癌变，导致肿瘤的发生。
DNA damage was an importance factor for mutation of cells, furthermore, carcinogen can be caused by severe mutation.
目的：观察木通所致大鼠肿瘤的发生演变过程、生物学行为、病理学及免疫组化特征。
Objective: To observe the oncogenetic process, biological behavior, pathological and immunohistochemical features of tumor induced by Aristolochia manshuriensis (AM) in rats.
结论CSS和CH单独作用均为肿瘤启动剂；当二者联合作用时可协同启动肿瘤的发生。
Conclusion Both CSS and CH may act as initiator in carcinogenesis, and may synergistically initiate tumors when CSS and CH were exposed simultaneously.
端粒是真核细胞线性染色体末端的一种特殊结构，与细胞的衰老及恶性肿瘤的发生密切相关。
Telomeres are linear chromosomal end special regions of eukaryotic cell and related intimately on the cells aging and the developing of malignant neoplasm.
在分子水平上，肿瘤的发生常涉及多基因参与，是一个多阶段、多步骤的复杂的生物学过程。
On the numerator level, the tumor often involves the gene of participation and it is a biology process that has many stages, and steps.
肿瘤的发生是原癌基因激活、抑癌基因失活以及凋亡相关基因失调等诸多因素综合作用的结果。
The development of tumor results from complex action among multiple factors such as oncogene activation, anti-oncogene inactivation, disturbance of apoptosis related gene and so on.
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