【Key words】 Chemical Industrial Park along the Yangtze River; organic extracts; in vitro; testicular cells; reproduction toxicity
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应用单细胞凝胶电泳技术,研究了烷基酚类化合物对离体小鼠睾丸细胞DNA的损伤作用。
The single cell gel electrophoresis technique (SCGE) was used to detecte the DNA damage of spermary cell in mice, which were induced by 9 tested environmental endocrine disrupting chemicals.
采用单细胞凝胶电泳检测小鼠睾丸细胞DNA受损程度,显示DNA迁移细胞数和彗尾长度上升。
DMA damage were detected by single-cell gel electrophoresis assay. After exposure the relative tail length of the comets and cells with DNA migration were increased.
研究结果提示,精索静脉曲张睾丸功能障碍可能与血清睾酮浓度低下及睾丸细胞核雄激素受体反应异常有关。
The authors suggest that the disturbed function of testes in rats with varicocele may be related to lower values of serum testosterone and abnormal reaction of NAR in testes.
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