方法获取10例淋巴瘤患者的活检淋巴结组织,以CGH技术检测淋巴瘤基因组d NA拷贝数的变化。
Methods Biopsy specimens of lymph nodes were obtained from 10 cases of lymphoma patients. The changes of DNA copies number (e. g. deletion and amplification) were detected using the CGH technique.
异常的超变和异常的致癌基因 BCL-6 与淋巴瘤的发生具有相关性。
Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 are associated with lymphomagenesis.
免疫组化及基因重排是诊断脑淋巴瘤重要工具。
Immunohistochemistry and gene rearrangement are important detective methods for brain lymphoma diagnosis.
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