方法获取10例淋巴瘤患者的活检淋巴结组织，以CGH技术检测淋巴瘤基因组d NA拷贝数的变化。
Methods Biopsy specimens of lymph nodes were obtained from 10 cases of lymphoma patients. The changes of DNA copies number (e. g. deletion and amplification) were detected using the CGH technique.
异常的超变和异常的致癌基因 BCL-6与淋巴瘤的发生具有相关性。
Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 are associated with lymphomagenesis.
免疫组化及基因重排是诊断脑淋巴瘤重要工具。
Immunohistochemistry and gene rearrangement are important detective methods for brain lymphoma diagnosis.
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗，联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
目的：探讨原发性皮肤间变性大细胞淋巴瘤(C - ALCL)临床病理特点和基因诊断方法。
Objective: To explore the clinicopathological features of primary cutaneous anaplastic large cell lymphoma (C-ALCL) and the significance of genetic analysis in the diagnosis.
科学家已经知道alk的异常和淋巴瘤还有肺癌的的发病有关。ALK的异常引起染色体之间DNA的置换，从而引起新的癌症基因的突变。
Scientists already knew that abnormalities in ALK were linked to lymphoma and lung cancer, where it triggers the translocation of DNA between chromosomes to make new cancer-causing genes.
目的研究LMP1基因和蛋白在结外鼻型NK/T细胞淋巴瘤移植瘤模型传代组织中的稳定性和变异性。
Objective To assess the stability and variability of the LMP1 gene and protein in nude-mice transplanted tumor models of extranodal nasal type NK/T-cell lymphoma.
研究发现，各型基因突变均可引起新生儿高胆红素血症、急性溶血性贫血等，也与病毒性肝炎、白血病、淋巴瘤等疾病的发生有一定关系。
Our Studies suggest that all the gene mutation may le AD to jaundice of the newborn, acute hemolytic anaemia, and have some relation to viral hepatitis, leukaemia, lymphoma.
细胞受体基因重排的检测在皮肤T细胞淋巴瘤的发病机制研究、分类、诊断、判断预后上有重要的作用。
The detection of TCR gene rearrangement has an important role in the study of the pathogenesis, classification, diagnosis and monitoring of prognosis of CTCL.
目的：研究癌基因在皮肤T细胞淋巴瘤中的作用。
Objective: To study the role of the oncogenes in cutaneous t cell lymphoma.
目的采用基因组杂交(CGH)技术，探讨淋巴瘤的分子遗传学特征。
Objective To explore the molecular genetic features of lymphoma by means of CGH (comparative genomic hybridization) technique.
目的研究免疫、基因在淋巴瘤分类中的作用。
Objective To study the role of immunity, gene in the classification in lymph tumors.
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
这些病例的临床病理特征表明，此类病变即使发生了克隆性igh基因重排，也不足以诊断淋巴瘤。
The clinical and pathologic features of these cases suggest that a clonal IGH rearrangement in this setting does not warrant a diagnosis of lymphoma.
目的研究皮下脂膜炎样T细胞淋巴瘤的临床病理特征、免疫表型、基因重排和预后。
Objective To study the clinicopathological features, the immunophenotyping, the gene rearrangement and the prognosis of subcutaneous panniculitis-like T-cell lymphoma (SPTCL).
克隆性免疫球蛋白重链基因重排检测可以作为诊断恶性B细胞性非霍奇金淋巴瘤的有效分子标志。
Clonal immunoglobulin heavy chain gene rearrangement can be used as a effective diagnostic molecular marker for B-NHL.
研究者同样看到了基因在如白血病和淋巴瘤中正常干细胞转化为癌变干细胞的可能作用。
The researchers also are looking into the possible role the gene plays in transforming healthy stem cells into cancerous ones, such as in leukemia and lymphomas.
目的研究b 71基因转染小鼠el4淋巴瘤细胞的致瘤性，为制备基因转染瘤苗提供实验依据。
Objective to study the Oncogenicity of rat EL4 lymphoma cell transfected with gene B71 and to provide experimental basis for preparing tumor vaccine by transfected gene.
目的：检测BLU与ARF基因启动子在鼻NK/T细胞淋巴瘤中的甲基化状态，探讨其在肿瘤发生中的作用与分子病理诊断中的应用价值。
AIM: To investigate the hypermethylation of the BLU and ARF promoter in nasal NK/T cell lymphoma from nasopharyngeal mucosa and its roles in tumor genesis and molecular pathological diagnosis.
异常的超变和异常的致癌基因BCL-6与淋巴瘤的发生具有相关性。
Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 is associated with lymphomagenesis.
仔细翻看556种已知的癌基因后，他们在40到49岁之间的341位病人身上发现只有不到百分之1的病人有19个白血病或淋巴瘤有关的基因有突变。
They looked closely at 556 known cancer genes. In 341 patients ages 40-49, fewer than 1 percent had mutations in 19 leukemia - or lymphoma-related genes.
他们将原癌基因诱导的淋巴瘤移植到野生型小鼠，然后在淋巴瘤细胞启动p53表达。
They transplanted Myc-driven lymphoma cells into wild-type mice and then turned on p53 expression in the lymphoma cells.
他们将原癌基因诱导的淋巴瘤移植到野生型小鼠，然后在淋巴瘤细胞启动p53表达。
They transplanted Myc-driven lymphoma cells into wild-type mice and then turned on p53 expression in the lymphoma cells.
应用推荐