本品是一种新型核苷酸类逆转录酶抑制剂。以与核苷类逆转录酶抑制剂类似的方法抑制逆转录酶，从而具有潜在的抗HIV-1活性。替诺福韦的活性成分替诺福韦双磷酸盐可通过直接竞争性地与天然脱氧核糖底物相结合而抑制病毒聚合酶，及通过插人DNA中终止链。
替诺福韦酯（Tenofovir disoproxil fumarate，TDF）是一种单磷酸腺苷的无环磷酸化的核苷酸类似物，其二磷酸盐是艾滋病和乙肝病毒逆转录酶抑制剂。
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产品中文名称 替诺福韦酯 产品英文名称 Tenofovir Disoproxil 产品中文异名 (R)-9-(2-磷酸甲氧基丙基)腺嘌呤二(异丙氧羰基氧甲基)酯;泰诺福韦酯; 产品英文异名 [[(2R)-1-(6-aminopurin-9
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富马酸替诺福韦酯 Tenofovir disoproxil fumarate ; Tenofovir disop
替诺福韦酯杂质XV Tenofovir Disoproxil impurity XV -Tenofovir disoproxil ; Tenofovir Disoproxil impurity XV
替诺福韦酯杂质XIV Tenofovir Disoproxil impurity XIV
替诺福韦酯杂质IX Tenofovir Disoproxil impurity IX
替诺福韦酯杂质XVI Tenofovir Disoproxil impurity XVI
替诺福韦酯杂质XII Tenofovir Disoproxil impurity XII
替诺福韦酯杂质I Tenofovir Disoproxil impurity ; Tenofovir Disoproxil impurity I MONO-POC PMPA
替诺福韦酯杂质A Tenofovir Disoproxil Related Compound
替诺福韦酯杂质X Tenofovir Disoproxil impurity
据业内人士介绍，替诺福韦酯在国际上是治疗艾滋病的最重要药物，也是国内急需的药品。
According to insiders, tenofovir ester in the international arena is the most important drugs to treat AIDS, is also badly needed medicines.
《国际肝病》： 2008年出台了修订版乙肝治疗指南，同年，富马酸替诺福韦酯（TDF）被FDA准许应用治疗慢性乙肝。
Hepatology Digest: In 2008, we saw the revised HBV Guidelines, the same year that TDF (tenofovir disoproxil fumarate) was approved for the treatment of chronic hepatitis B by the FDA.
在所得的溶液(1)的色谱图中，与替诺福韦酯相关的任何色谱峰的峰面积应不大于溶液(2)色谱图中主峰峰面积的2倍(1.0%)。
In the chromatogram obtained with solution (1), the area of any peak due to the tenofovir monoester is not greater than twice the area of the principal peak obtained with solution (2) (1.0%).
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