我对我的问题感到孤单无依，苦恼不已。

I feel very alone and distressed about my problem.

《柯林斯英汉双解大词典》

他对自己的体重感到有点儿苦恼。

He's a little touchy about his weight.

《牛津词典》

对任何一个感到与世界的命运紧密相连的人，文明的冲突有种让他苦恼的东西。

For anyone who feels bound up with this world's fate, the clash of civilizations has something agonizing about it.

youdao

Unless the philosophers rule as kings or those now called kings, genuinely philosophize, there will be no rest from the ills for the cities, ?! he says, right?

除非让哲学家为王统治,或现时为王者，真诚地开始哲思，不然城市中的苦恼将永不止息，他这么强调，对吧？

耶鲁公开课 - 政治哲学导论课程节选