目的:CTCF是一种多功能的转录因子,参与启动子调控、绝缘子功能和遗传印记等过程。
Objective: CTCF is a multifunctional transcription factor, which plays many roles in promoter regulation, insulator function and genetic imprinting.
提示- 1892和- 1837两位点虽不在启动子区,但可能对靶基因表达具有一定的远端调控作用。
It suggests that although -1892 and -1837 loci are far from the promoter, they may play a remote regulation on the target gene expression.
本论文工作着重进行人acat - 1基因P 7启动子活性调控和脂肪酸对人acat 1基因表达影响的两部分探索。
This work was mainly focused on the transcriptional regulation of human ACAT-1 gene P7 promoter activity, and the effect of fatty acids on human ACAT1 gene expression.
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