• 目的CTCF一种多功能转录因子参与启动调控绝缘子功能遗传印记等过程

    Objective: CTCF is a multifunctional transcription factor, which plays many roles in promoter regulation, insulator function and genetic imprinting.

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  • 提示- 1892- 1837两位点虽不在启动子区,可能基因表达具有一定的远端调控作用

    It suggests that although -1892 and -1837 loci are far from the promoter, they may play a remote regulation on the target gene expression.

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  • 论文工作着重进行acat - 1基因P 7启动活性调控脂肪酸人acat 1基因表达影响两部分探索。

    This work was mainly focused on the transcriptional regulation of human ACAT-1 gene P7 promoter activity, and the effect of fatty acids on human ACAT1 gene expression.

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  • 负责执行这个调控过程组成成分包括及其启动酶系统蛋白酶体系统

    Components in charge of this process include ubiquitin, its startup enzymes, and proteasome system.

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  • 启动成功克隆其报告基因载体构建,研究SOD2的基因表达调控机制提供了重要基础工具

    The reporter gene vector driven by SOD2 promoter will provide an experimental tool for the further study on the regulatory mechanism of the SOD2 expression.

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  • 通过P25基因启动活性分析尤其是对PS GFBMFA调控元件的功能分析,有利于进一步了解P 25基因表达调控精细机制

    Analysis of P25 promoter activity, especially functional analysis of PSGF and BMFA regulatory elements, could be helpful in further understanding the mechanism of P25 expression and fine regulation.

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  • TNNI2TNNI 3启动调控元件保守调控元件差异其中TNNI 1子存在。

    The regulatory elements in the proximal promoter of TNNI2 and TNNI3 were conserved among human, mouse, and pig, but regulatory element differences existed in the TNNI1 promoter among them.

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  • 结论EBV相关胃癌EBV阳性鼻咽癌组织病毒潜伏期基因启动甲基状态不同,甲基化调控EBV潜伏期基因启动活动重要机制之一

    Conclusion The methylation status of EBV latent gene promoters in EBVaGC and NPC is different, methylation is one of important mechanisms in regularing the activity of EBV latent gene promoters.

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  • 在NOS1基因启动子区鉴定了调控区域两个调控区域,同时TS A上调不同长度启动转录活性

    Two positive regulation regions and two negative regulation regions were found within NOS1 promoter. TSA may up-regulate the transcription activities of NOS1 promoters of different length.

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  • 凝胶ZND是否能够形成隔断地层流体井筒流体联系隔断式凝胶塞,所形成的凝胶段塞是否具有启动压力梯度及其调控措施实验现场试验证实;

    However, it was still lack of systematic study of rheology of gel ZND. And the rationality, correctness and feasibility of the separating-type gel slug principle need to be verified yet.

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  • 启动基因表达调控关键性作用在很大程度上决定所基因表达的时间空间强度。

    Promoter plays a key role not only in regulating the level of gene expression but also in controlling the expression in a spatial and temporal manner.

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  • 启动基因表达调控关键性作用在很大程度上决定所基因表达的时间空间强度。

    Promoter plays a key role not only in regulating the level of gene expression but also in controlling the expression in a spatial and temporal manner.

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