针刺对吗啡戒断大鼠情绪及氨基酸水平的影响_医学论文 关键词】 吗啡戒断 焦虑 甘氨酸 谷氨酸 γ氨基丁酸 针刺 [gap=1103]Key words】 morphine withdrawal,anxiety,glycine,glutamate,GABA,acupuncture
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吗啡戒断大鼠 morphine withdrawal rat
The neuroadaptations observed during morphine withdrawal in this study could be important neuronal substrates mediating reinstatement of drug seeking behavior, which could also be one of the causes underlying the reduction of rewarding effect of natural rewards during drug withdrawal.
本研究发现的吗啡戒断时伏核的这些变化可能是觅药行为复燃的重要神经底物和药物戒断时自然奖赏因素效力下降的原因之一。
参考来源 - 吗啡戒断大鼠伏核神经元兴奋性的改变·2,447,543篇论文数据,部分数据来源于NoteExpress
目的观察褪黑激素(MT)对小鼠吗啡戒断反应及血浆、脑组织中NO含量的影响。
AIM to observe the effect of melatonin (MT) on morphine withdrawal syndromes and determine the content of NO in plasma and brain tissue in morphine dependent mice.
结论:针刺通过抑制NOS活力与NO生成,在改善吗啡戒断症状过程中起到良性调节作用。
Conclusion: Acupunctureplay good regulation role in the course of improving morphine abstinence syndrome by inhibiting NOS activity and decreasing NO production.
方法:按照逐日递增原则给予小鼠皮下注射吗啡,以纳洛酮催瘾,建立吗啡戒断后焦虑动物模型。
Methods: The anxiety mice model was formed based on the principle of morphine increase progressively day by day, in which after the mice were induced into morphine dependence, naloxone was given.
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