但是鼠抗独特型抗体,作为疫苗反复应用于人体可诱导人抗鼠抗体(human anti-mouse antibody,HAMA)的产生。同时抗独特型抗体只模拟少数表位,免疫原性弱,应用时还需要佐剂。
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...:肿瘤导向治疗中,由于所用鼠源性抗体的分子量大、免疫原性强、半衰期长及反复应用易产生人抗鼠抗体(human anti-murine antibody,HAMA)反应等弊端,使其在临床的应用受到很大限制。
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人抗鼠抗体试剂盒 Human antimous antibody,HAMA ELISA KIT
人抗鼠抗体反应 human anti-mouse antibody ; HAMA ; human antimurine antibody response ; human anti-mouse antibody response
产生人抗鼠抗体 Human antigen mouse antibody
引发人抗鼠抗体 human antimurine antibodies
人抗小鼠抗体 human anti-mouse antibody ; HAMA
产生人抗小鼠抗体 human anti-mouse antibody ; HAMA
鼠抗人HCG抗体 alfa-HCG Antibody-Biotin
人抗鼠的抗体 human anti-mouse antibody
为了降低人抗鼠抗体反应,获得满意的免疫原性,将模拟人卵巢癌抗原的抗独特型单链抗体人源化。
In order to reduce the human anti mouse antibody response and obtain optimal antigenicity, anti idiotype single chain which mimicking ovarian cancer antigen has been humanized.
SCID鼠移植细胞3个月后用鼠抗人白蛋白抗体检测小鼠肝脏中的人白蛋白,可见有点状或小灶状表达。
Dotted or small focal expressions were found in SCID mouse liver when detecting the human serum albumin with mouse anti-human albumin antibody after transplantation of the stem cells in 3 months.
采用D2C5 6细胞株表达并提纯抗CD71人鼠嵌合抗体;
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