为了降低人抗鼠抗体反应,获得满意的免疫原性,将模拟人卵巢癌抗原的抗独特型单链抗体人源化。
In order to reduce the human anti mouse antibody response and obtain optimal antigenicity, anti idiotype single chain which mimicking ovarian cancer antigen has been humanized.
SCID鼠移植细胞3个月后用鼠抗人白蛋白抗体检测小鼠肝脏中的人白蛋白,可见有点状或小灶状表达。
Dotted or small focal expressions were found in SCID mouse liver when detecting the human serum albumin with mouse anti-human albumin antibody after transplantation of the stem cells in 3 months.
采用D2C5 6细胞株表达并提纯抗CD71人鼠嵌合抗体;
抗粘附治疗是新兴的一种治疗方法,但单抗鼠源性限制其应用、人抗体研究的突破为抗粘附治疗的临床应用铺平了道路。
Anti adhesion therapy is novel, but it is restricted by the murine quality of monoclonal antibody. The breakthrough of human antibody paves the way to clinical anti adhesion therapy.
抗体人源化检测显示,只能被羊抗人抗体识别,不能被羊抗鼠抗体识别。
The expressed product can only be recognized by goat-anti-human antibody rather than goat-anti-mouse antibody.
抗体人源化检测显示,只能被羊抗人抗体识别,不能被羊抗鼠抗体识别。
The expressed product can only be recognized by goat-anti-human antibody rather than goat-anti-mouse antibody.
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