Being single comes with ups and downs.

单身的心情也是起起落落的。

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Life can be one giant conundrum filled with ups and downs.

人生就是一个巨大的谜题，充满了起起伏伏。

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They are part of a built-in mechanism, which allows us to cope with the ups and downs of our lives both physically and mentally.

它们是一种内在机制的组成部分，使我们能够在身体和精神上应对生活的起起落落。

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It is going to have ups and downs." Iranians are moving towards a closer relationship with the rest of the world, even against their own government.

VOA: standard.2010.06.15

History is repeating itself so far in 2011, which has been fraught with ups and downs in both international and domestic equity markets.

FORBES: Watch Out: 2011 Looks A Lot Like The Market Top In 2007

Novartis may be wise to seek a measure of stability in an industry beset with ups and downs, but it could experience some unwelcome side-effects.

ECONOMIST: The best medicine? | The

The year 2011 was one of the most volatile ever for stocks, with ups and downs nearly as severe as during the financial crisis of three years ago.

FORBES: 2011: A Scary Year For Stocks, And Not The Last