瘤 【中文名称】：司坦夫定 【英文名称】：Strvudine 【类别】：抗感染药 【说明】：【别名】司坦夫定 , 赛瑞特,司他夫定 【外文名】Zerit ,Strvudine, d4T 【药理毒理】司坦夫
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Pure stavudine was recrystallized in suitable solvent and the yield was increased by 52.3%-57.2%.
生成司它夫定的粗品，本文寻找了合适的重结晶溶剂成功提纯了司他夫定，总收率57.2％较过去52.3％略有提高。
参考来源 - 抗艾滋病药物齐多夫定、司它夫定与功能分子异硬脂酸合成研究·2,447,543篇论文数据，部分数据来源于NoteExpress
A few drugs have harmful effects when used together and should not be combined (an example is stavudine and zidovudine).
某药物一起使用时的会产生有害影响，不应组合使用(例如司他夫定和齐多夫定)。
Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended.
齐多夫定会竞争性抑制司他夫定的磷酸酰化，因此禁止与齐多夫定联合用药。
The stavudine was prepared from 5-methyluridine via six steps in 34% overall yield, in which the key step is the selective acylation of 5-methyluridine by propionyl chloride.
该路线以5-甲基尿苷为起始原料，关键步骤是5-甲基尿苷和丙酰氯的选择性酰化反应，六步反应总收率为34%。
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