β分泌酶原核表达载体的构建、表达及融合蛋白纯化-临床医学论文-中国论文联盟 关键词】 β分泌酶;大肠杆菌;表达;融合蛋白 [gap=911]Key words】βsecretase; E. coli; Expression; Fusion protein
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细胞制造一个「前淀粉样蛋白APP(Amyloid Precursor Protein),后者会被分泌素(Secretase)转为一个叫C99的蛋白质,以协助细胞感应细胞外胆固醇的分量(Biochemistry, Vol.47, pp.9428-9446);若分泌素出了问题,会抑制一...
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gamma-secretase 分泌酶
Beta-Secretase 贝塔分泌脢 ; 乙型分泌素
Secretase inhibitor 分泌酶抑制剂
a-secretase 分泌酶
gamma-secretase inhibitors 分泌酶抑制剂
Y-secretase 分泌酶
secretase of amyloid precursor protein 淀粉样前体蛋白分泌酶
gamma secretase inhibitor 分泌酶抑制剂
The generation of Aβfrom the amyloid precursor protein(APP) is initiated byβ-secretase(β-site of APP-cleaving enzyme,BACE1).
β-分泌酶(β-site of APP-cleavingenzyme,BACE1)是酶切淀粉样前体蛋白(amyloid precursor protein,APP),生成Aβ的关键酶。
参考来源 - β·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.
当一种叫淀粉样前体蛋白(APP)的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。
For the past decade there has been a lot of work on drugs called secretase inhibitors, which alter the activity of the enzymes that create amyloid beta-peptide 42.
在过去的10年里人们对被称为分泌酶抑制剂的药物进行了大量研究,这种药物可以改变酶类产生淀粉样贝塔-肽42的活动。
Eberhart and colleagues studied glioblastoma cell lines to investigate the effects of a gamma-secretase inhibitor, a medication that blocks the Notch receptor, on tumor growth.
埃伯哈特和他的同事们研究了恶性胶质瘤的细胞系以发现γ-内分泌酶抑制剂的影响,这种药物可阻断促使肿瘤增长的Notch受体途径。
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