The vast majority (86.8%) of trials were open-label, while only 13.2% used blinding.

绝大部分的临床试验（86.8%）属于开放性的，只有13.2%的临床试验采用了盲法设计；

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Taxanes versus S-1 as the first-line chemotherapy for metastatic breast cancer (SELECT BC): an open-label, non-inferiority, randomised phase 3 trial.

紫杉醇与S-1作为转移性乳腺癌的一线化疗（选择BC）：一项开放标签、非劣效性、随机3期试验。

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During a blinded period, patients received active or sham stimulation, followed by an open-label phase in which all the patients received active stimulation.

在盲性治疗期内，患者分别接受阳性刺激或假刺激，然后在开放性治疗期内，所有患者均接受阳性刺激。

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The study was a multinational, single-arm, open-label, 78 week trial that was recently published in the November 2, 2012 online version of the Lancet.

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Schneider CK, Melmed RD, Barstow LE, Enriquez FJ, Ranger-Moore J, Ostrem JA. Oral Human Immunoglobulin for Children with Autism and Gastrointestinal Dysfunction: A Prospective, Open-Label Study.

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Obviously, an unblinded trial design (also known as an open-label trial) represents a particularly high-risk approach when the outcome involves a subjective assessment by either the patient or the physician.

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