Methods: Patients with CCMD-3-diagnosed schizophrenia requiring antipsychotic treatment were randomly assigned to open-label oral quetiapine or haloperidol decanoate for 21days.

方法符合CCMD - 3诊断标准的精神分裂症住院患者，采用随机对照、开放性研究治疗21天。

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The vast majority (86.8%) of trials were open-label, while only 13.2% used blinding.

绝大部分的临床试验（86.8%）属于开放性的，只有13.2%的临床试验采用了盲法设计；

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To verify the curative effect and safety of lamotrigine (LTG) for the treatment of childhood epilepsy, a open-label, add-on, self-control study was undertaken on 44 children with intractable epilepsy.

为验证拉莫三嗪治疗儿童癫痫的疗效和安全性，对44例儿童顽固性癫痫进行了开放性自身对照研究。

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Despite some limitations of trial design, including the open label nature of the study, RECORD remains the only randomized trial of cardiovascular outcomes for Avandia at this time.

FORBES: Glaxo Alleges Errors In Nissen's Critique Of FDA's Handling Of Avandia

The study was a multinational, single-arm, open-label, 78 week trial that was recently published in the November 2, 2012 online version of the Lancet.

FORBES: FDA Approves Lomitapide For Homozygous Familial Hypercholesterolemia

Schneider CK, Melmed RD, Barstow LE, Enriquez FJ, Ranger-Moore J, Ostrem JA. Oral Human Immunoglobulin for Children with Autism and Gastrointestinal Dysfunction: A Prospective, Open-Label Study.

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