High mobility group box 1 (HMGB1), a 30 kD non histone chromatin-associated protein, is extremely conserved across species. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription.
高迁移组蛋白1(high mobility group box 1,HMGB1),分子量约30 kD,为一进化相当保守的非组蛋白染色质结合蛋白,在细胞内参与稳定核小体,促进基因转录。
参考来源 - 高迁移组蛋白1诱导大鼠肺泡巨噬细胞表达诱生型一氧化氮合酶的机制及其在急性肺损伤发生中的作用·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
N a repeating structural unit of chromatin that contains DNA and histones 核小体
As the genetic blueprint of life, DNA must be deciphered or "read," even when densely packed into nucleosomes.
DNA作为生命的遗传蓝图,必须被解码或被“阅读”,甚至在被紧密“打包”放进核小体的时候也是如此。
RNA synthesis can proceed through nucleosomes.
RNA的合成在核小体上进行。
Solenoid --- A fiber composed of compacted strings of nucleosomes, forming the fundamental unit of chromatin organization.
核小体串珠压缩整合而成的一种纤维结构,形成染色质结构的功能单位。
应用推荐