They found that when NRF2 was missing, the process of translating messages from the genes into proteins was highly affected by the oxidant and antioxidant balance, but only in the cancerous cells.
他们发现当NRF2消失时,将基因信息翻译变成蛋白质的过程在很大程度上受氧化剂和抗氧化剂之间平衡的影响,但仅限于癌细胞。
When NRF2 is active, cells synthesize a chemical called glutathione, an important antioxidant.
当NRF2活跃时,细胞能合成一种化学物质叫谷胱甘肽,一种重要的抗氧化剂。
Products made by a gene called NRF2 normally protect cells from environmental pollutants like cigarette smoke and diesel exhaust by absorbing the materials and pumping them out of the cell.
由NRF2基因表达的产物通常通过吸收和泵出细胞的方式,防止香烟及柴油废气等环境污染物对细胞的损害。
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