When NRF2 is active, cells synthesize a chemical called glutathione, an important antioxidant.
当NRF2活跃时，细胞能合成一种化学物质叫谷胱甘肽，一种重要的抗氧化剂。
In cancer cells, NRF2 activity runs amok, sweeping away all cellular toxins, including chemotherapy agents.
在癌细胞上，NRF 2活性疯狂增强，细胞内的毒素包括化疗药物被彻底清除。
The team wanted to combine this with the BSO to mimic what would happen if they could reduce levels of NRF2.
研究团队试图将其同bso联用，如果在他们能减少NRF 2水平的情况下，看能发生什么情况。
To halt the detox process, proteins manufactured by KEAP1 bind to the NRF2 triggers tagging them for destruction.
为了阻止这个解毒过程，由KEAP1生成的蛋白质结合到NRF 2触发器上，破坏NRF2作用。
They concentrated on NRF2, a protein that can be tweaked to disrupt the balance between oxidation and decreased cancer cells.
他们将注意力集中在NRF2上，一种能够通过微调来打乱氧化剂间平衡，从而减少癌细胞的蛋白。
NRF2 activity along with its cleansing proteins and enzymes were higher in tumor samples than normal cells, according to the researchers.
研究者报道，NRF 2活性及其它的纯化蛋白和酶肿瘤标本中高于正常细胞。
Products made by a gene called NRF2 normally protect cells from environmental pollutants like cigarette smoke and diesel exhaust by absorbing the materials and pumping them out of the cell.
由NRF2基因表达的产物通常通过吸收和泵出细胞的方式，防止香烟及柴油废气等环境污染物对细胞的损害。
They found that when NRF2 was missing, the process of translating messages from the genes into proteins was highly affected by the oxidant and antioxidant balance, but only in the cancerous cells.
他们发现当NRF2消失时，将基因信息翻译变成蛋白质的过程在很大程度上受氧化剂和抗氧化剂之间平衡的影响，但仅限于癌细胞。
They found that when NRF2 was missing, the process of translating messages from the genes into proteins was highly affected by the oxidant and antioxidant balance, but only in the cancerous cells.
他们发现当NRF2消失时，将基因信息翻译变成蛋白质的过程在很大程度上受氧化剂和抗氧化剂之间平衡的影响，但仅限于癌细胞。
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