In order to meet the demands and expectations of oncologists, regulators and payers, the sponsor of the next ALK inhibitor will need to prove not only that its drug is effective, but the sponsor also will need to run comparator studies of its new drug against Xalkori.

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Like any game, multiplayer games will need to prove that they can provide engrossing, entertaining experiences.

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To make a normal murder charge stick, prosecutors need to prove the defendant intended to kill.

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