In order to meet the demands and expectations of oncologists, regulators and payers, the sponsor of the next ALK inhibitor will need to prove not only that its drug is effective, but the sponsor also will need to run comparator studies of its new drug against Xalkori.
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Like any game, multiplayer games will need to prove that they can provide engrossing, entertaining experiences.
To make a normal murder charge stick, prosecutors need to prove the defendant intended to kill.
It begs the question: when does a man no longer feel the need to prove himself?
Mr Coll suggests that, isolated among half-brothers, he always had a need to prove himself.
Depending on the state, supervisors will need to prove a minimum level of education and immunization from disease.
And he will need to prove that he can manage a national emergency without being distracted by politics.
Such penalties should be set out in a statute and there should be no need to prove actual damage.
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Finally you need to prove the platform is profitable for third party developers.
Maybe Zuckerberg, sitting on the verge of a blockbuster stock offering, no longer feels the need to prove himself.
Under the principle, prosecutors need not prove who inflicted the fatal wound - only who played a part in the incident.
But Irvine, who will manage the tour, warned that Henson would need to prove that he is fully committed to rugby.
Crucially, however, prosecutors may no longer need to prove the power of authority in a bribery case to secure a conviction.
But definitely in Formula One every year you need to prove yourself.
Facebook, since going public, has had a tendency to give back gains soon after any bounces, and it will need to prove itself.
Lohan would also need to prove that the ad implied her endorsement and was not simply a parody, which is protected by law.
Woo's producing partner, Chang, says the need to prove box-office appeal has slowed Woo's creative progression from where he left off in Hong Kong.
The researchers need to prove that the 10 classifications actually provide any benefit to people with breast cancer, before they can be used by doctors.
Even if you are Michael Schumacher, you need to prove yourself.
Then, they need to prove that they can tap into long-term credit markets without leaning on the Federal Deposit Insurance Corp. to guarantee their debt.
He told me the sequester is going to go through, at least for a few days, because both sides need to prove how tough they are.
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The plaintiffs did not need to prove criminal charges to claim compensation, stressed Sir Declan, just that they had been harmed by personal injury or trespass.
Anyone under 16 has to be accompanied by an adult and people aged 18 and over need need to prove they are old enough to accompany a youngster.
Henson will now need to prove himself during the early games of Swansea's Heineken Cup campaign if he is to have any realistic chance of facing the Irish.
To get patent protection under India's laws, companies need to prove that new versions of their products are therapeutically more beneficial than earlier versions on which patents have expired.
Ignoring accounting benefits, Accelrys will still need to prove to investors that it can extract value from being the early leader in chem-informatics and nanoscale modeling and simulation software.
The judge reserved the right to downgrade his ruling at any time, but Mr Pistorius' legal team will now need to prove he deserves bail despite facing the most serious charge.
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