Excessive ozone in the air can have a marked effect on human health.

空气中过多的臭氧对人类健康造成显著影响。

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How to produce a marked effect of laboratories in teaching and serve for teaching better?

如何发挥实验室在教学中的重要作用，更好地为教学服务呢？

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Under different Angle lean-state, the initial drawback makes a marked effect on buckling bearing capacity of piston.

活塞在不同倾斜度下，初始缺陷对活塞屈曲承载力的影响较大。

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This had a marked effect on the size of the treated tumour, and also seemed to encourage tumour regression in other parts of the body.

BBC: NEWS | Health | Immune boost 'widens cancer fight'

"All of the updated data that we have collated supports the conclusion that claims management companies have had a marked effect on the number of small injury, whiplash-like claims, " said David Brown, chairman of the actuaries' professional body.

BBC: Traffic

The first open skies agreement, which came into effect in 2008, marked a significant step in the liberalisation of the transatlantic airline industry.

BBC: Second open skies deal signed