This is the one major drawback of the new system.

这是新系统的一大弊端。

《牛津词典》

A major drawback of vertical farming, however, is that the plants would require artificial light.

然而，垂直种植的一个主要缺点是，这些植物需要人工照明。

youdao

Unfortunately, it has one major drawback.

不幸的是，它也有一个主要缺点。

youdao

One major drawback, however, was the amount of time and work that was needed to prepare a sample.

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The extreme inequality in the distribution of income remains a major drawback.

FORBES: Lesotho

"The major drawback of flying compared to train travel is, of course, the time spent at the airport, " says ANA spokesman Ryosei Nomura.

BBC: Near field communication transforms travel in Japan