This is the one major drawback of the new system.
这是新系统的一大弊端。
A major drawback of vertical farming, however, is that the plants would require artificial light.
然而，垂直种植的一个主要缺点是，这些植物需要人工照明。
Unfortunately, it has one major drawback.
不幸的是，它也有一个主要缺点。
The major drawback with the iPhone is the phone service.
iPhone最大的缺点就是它的通话服务。
As our project evolved, I found that this approach had a major drawback.
随着我们项目的进展，我发现这种方法有一个重要缺陷。
The high cost is a major drawback.
高成本是主要的障碍。
A major drawback of sales promotion is that it is easily copied by competition.
销售促销的一个大缺点是很容易被竞争对手模仿。
However, a major drawback for now is the lack of a national antibodydatabase.
然而，目前一个主要的不利点是缺乏全国性抗体数据库。
Unfortunately, using dynamic proxy classes does have one major drawback: performance.
不幸的是，使用动态代理类确实有一个重要不足：性能。
That version suffered from one major drawback: it tied a class to particular aspects.
版本3有一个很大的缺点：它使一个类与特定的方面关联在一起。
Another major drawback of JSONP is that it can be quite dangerous if used with untrusted services.
JSONP的另一个主要缺陷是被不信任的服务使用时会很危险。
The major drawback is that a college degree requires a huge investment in time, money, and mental effort.
这一方法的主要缺点是取得学位需要花费大量的时间，金钱和努力。
The major drawback to this cloud is the difficulty in effectively creating and governing such a solution.
该云的主要缺陷是很难有效创建和管理此类解决方案。
So far, so good, but there's a major drawback: CDT as it currently stands cannot explain the existence of matter.
到目前为止，这个理论都很好，但是有一个最主要的缺点：目前的CDT并不能解释物质的存在。
The major drawback is the poor stability of materials if shaped in elements smaller than 10 nanometres in size.
主要的缺点是材料的尺寸小于10纳米后，其稳定性就很差。
All of the XML binding APIs share a major drawback with the manual serialization technique: the coupling of model and view.
所有的xml绑定api都具有手工序列化技术的一个主要不足：模型和视图的耦合。
A major drawback of this built-in function, however, has been its inability to automate the collection of such information.
但是这种内置功能有一个很大的缺陷，它不能自动收集这样的信息。
A state machine has a major drawback: It is only useful for visualizing workflows at the macro level of application interactions.
状态机的一个主要缺点是：它只对应用程序交互的宏观层次的可视化工作流有用。
This has a great impact on performance, but there is one major drawback: the clients do not immediately recognize changes made to the rules.
这对性能有很大的影响，但是有一个主要的缺点：客户机不能立即识别对规则的更改。
While cisplatin is often effective when first given, it has a major drawback: Tumors can become resistant to the drug and start growing again.
顺铂通常第一次给药时有效，它有一个主要的缺陷：肿瘤获得耐药性，而且重新开始生长。
One major drawback is that it's a single-system solution, which is fine if you want to manage your Perl installations on a single-computer basis.
主要缺点之一就是它是单系统解决方案，如果以单一计算机为基础来管理Perl安装，那么这个解决方案很好。
Unfortunately, the relatively low sensitivity of sputum smear microscopy - even more so in the presence of HIV co-infection - is a major drawback to case-finding.
不幸的是，痰涂片镜检的敏感性相对较低，对于合并感染艾滋病毒的患者则更低，这是病例发现方面的一个重大障碍。
A major drawback of block discrete cosine transform (BDCT) is that the decoded images, especially at very low bit rates, exhibit highly noticeable blocking artifacts near the block boundaries.
为了减少低比特率时块离散余弦变换(BDCT)在块边界所出现的明显可见的方块效应，提出了一种新的DCT域的去块效应消除算法。
The major drawback of being a gene delivery vector is the low efficiency of transfection, so the scientists have been trying to increase the efficiency of chitosan with the methods of modifications.
壳聚糖作为基因载体的主要缺陷是转基因效率比较低，所以研究者们试图通过修饰以增加壳聚糖的转基因效率。
The major drawback of being a gene delivery vector is the low efficiency of transfection, so the scientists have been trying to increase the efficiency of chitosan with the methods of modifications.
壳聚糖作为基因载体的主要缺陷是转基因效率比较低，所以研究者们试图通过修饰以增加壳聚糖的转基因效率。
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