...蝶呤治疗儿童急性淋巴细胞白血病的疗效与安全性分析 孟岩 【摘要】： 目的:大剂量甲氨蝶呤(high-dose methotrexate , HD-MTX)是儿童急性淋巴细胞白血病(Acute lymphoblastic leukemia, ALL,简称急...
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Objective To study the clinic features and the mechanism of skin damage induced by high-dose methotrexate (HD-MTX).
目的了解大剂量氨甲蝶呤(HD - MTX)化疗引起皮肤损伤的临床特征，并探讨其发生机制。
Method Children treated with HD-MTX were enrolled in a retrospective study in which the incidence and presentations of skin damage were concluded.
方法总结儿童HD - MT X化疗致皮肤损伤的临床表现，并分析其发病机制。
Objective:To analyse the adverse drug reaction of high dose methotrexate (HD-MTX) in treatment of childhood acute lymphoblastic extramedullary leukemia (ALL).
目的：剖析比拟出口与国产甲氨蝶呤（HD-MTX）在预防治疗儿童急性淋巴细胞髓外白血病进程中不良反响的发作率。
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