【first_pass_effect】什么意思_英语first_pass_effect的翻译_音标_读音_用法_例句_在线翻译

first pass effect

首过效应

11、首过效应（first pass effect）：药物位置肠道吸收过程中，在消化道和肝脏中发生药物代谢，使进入体循环原形药量减少的现象。

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首关效应

1、 首关效应 （ first pass effect ）：各种给药途径的吸收过程不同。口服给药主要在肠道内吸收，通过毛细血管，进入肝门静脉。

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首渡效应

首渡效应(First pass effect) ：口服药物经肠胃道吸收后，会先经由肠肝循环，经过肝脏代谢后，才由肝门静脉回到心脏，之后才经由动脉的血液循环到全身各处，发...

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短语

first-pass effect 首关效应 ; 首过效应

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医药科学

·2,447,543篇论文数据，部分数据来源于NoteExpress

abstract: The first-pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation. It is the fraction of lost drug during the process of absorption which is generally related to the liver and gut wall.

以上来源于: WordNet

Objective: To explore the first-pass effect in Small intestine.

目的：探讨小肠在首过效应中的作用。

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Documents show that the low biological activity of quercetin is due to its low bioavailability. Poor solubility and first-pass effect are the main factors that affect its bioavailability.

文献表明槲皮素生物活性低是由于其低的生物利用度，溶解性差与首过效应是影响其生物利用度的主要因素。

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ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.

结论DBDCT在大鼠肝微粒体中代谢较快，提示该药可能肝首过效应较强。

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