We can't go on like this— something's got to give.

我们不能继续这样了—得作一些改变。

《牛津词典》

Whatever the reason, one thing's for sure — something's got to give.

无论是什么原因，有一件事是肯定的---毕竟都有所付出。

youdao

Something's got to give and, sadly, my husband gets bumped way down the list.

有些东西必须给与，可悲的是我丈夫就成了最不受关注的对象。

youdao

With all this thumbing, something's got to give and in Yuzawa's case it's reading.

CNN: ASIANOW - TIME Asia | Japan's Mobile-Phone Culture

Mr. LEE: (Singing) Something's got to give with the way I'm living.

NPR: Folk-Soul Singer Amos Lee in Concert

Something's got to give.

WSJ: Andy Kessler: Professors Are About to Get an Online Education