She lost heart and gave up her dream.

她失去了信心，放弃了梦想。

youdao

I was afraid Bill might have forever lost heart.

我担心比尔会永远失去信心。

youdao

I lost heart and had no idea what I would become.

我灰心了，不知道我要成为什么样的人。

youdao

As his friends noticed, he had lost heart for revelry.

NEWYORKER: Rich Man, Poor Man

When I got the news I lost my mind, I lost my heart and the whole world collapsed for me.

BBC: Pakistan's 'haunting' Taliban problem

"When the merchants of Hamidiya -- the main souq (marketplace) -- go on strike, you know you have lost the conscience and heart of Damascus, " wrote Joshua Landis, a Syria expert and director of the Center for Middle East Studies at the University of Oklahoma.

CNN: Syria: Battle for the cities