Comparing with fed-batch fermentation with batch feeding, the potency and fermentation index of fed-batch fermentation with continuous feeding was increased by 13.5% and 12.5%, respectively. The highest potency of fed-batch fermentation with continuous feeding in 50M3 fermentor reached 5700u/ml.
流加补料发酵可避免分批补料发酵因培养环境的突然改变给菌体带来的不良影响，与分批补料发酵相比，采用流加补料发酵方法可以使螺旋霉素发酵单位提高13.5％，发酵指数提高12.5％，最高放罐效价达到5700u／ml。
参考来源 - 螺旋霉素高产菌种选育及发酵工艺优化In the pH-stat fed-batch fermentation,the highest OD_(600) was 98,the FDH enzyme activity was 12.1U/ml.
在pH-stat法补料发酵方式下,菌体最终OD_(600)达到98,发酵液中FDH酶总活力达到12.1U/ml。
参考来源 - 甲酸脱氢酶基因的克隆表达及重组菌的高密度培养In addition, a compartment model was proposed to describe the time courses of cell growth and the synthesis of SAM and GSH in fed-batch fermentation.
另外，还构建了一个室模型来描述酿酒酵母流加发酵生产SAM和GSH过程。
参考来源 - 酿酒酵母流加发酵同时生产SIn the research of fermentation process optimal control method, a run-to-run optimization exploits the repetitive nature of fed-batch processes in order to deal with the optimal problems of fed-batch fermentation process with inaccurate process model and unsteady process state.
在发酵过程优化控制方法研究上,针对批次发酵过程模型不准确和过程参数不稳定特点,利用批次流加过程中的反复迭代特性提出一种用于批次流加发酵过程的批次间协同优化控制方法。
参考来源 - 群能量守恒粒子群算法及其在发酵过程控制中的应用研究·2,447,543篇论文数据，部分数据来源于NoteExpress
The fed-batch fermentation method was studied by flask culture based on the optimal medium.
然后在该培养基配方的基础上进行摇瓶分批补料发酵试验，确定最佳补料方案。
Utilization ratio on raw material could increase from 82.62% to 88.51% in fed-batch fermentation.
采用分批补料的供糖方式的发酵可将原料利用率从82.62%提高到88.51%。
Experimental studies were carried out on the fed-batch fermentation process of sorbose in a 16l airlift reactor.
在全容积16l的环隙气升式反应器内，进行了高浓度山梨糖流加发酵过程的研究。
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