Arsenic causes carcinogenicity on human skin through inhibiting the expressions of MGMT, XRCC1 and influencing the genetic stability and the DNA repair function.
砷可能通过抑制砷中毒患者皮肤组织中MGMT、XRCC1等DNA修复基因的表达,影响基因组d NA稳定性和DNA修复功能而导致对皮肤的致癌作用。
BRCA1 protein forms at least three distinct complexes (BRCA1 a, B, and c) with other DNA repair proteins, and these interactions are vital for regulation of BRCA1 function.
BRCA1会和其他DNA损伤蛋白结合形成至少三种不同的复合物(BRCA1A, B和C),这种结合对于调控BRCA1的功能是至关重要的。
BRCA1 forms at least three distinct complexes (BRCA1 a, B, and c) with other DNA repair proteins, and these interactions are vital for the regulation of BRCA1 function.
BRCA1会和其他DNA损伤蛋白结合形成至少三种不同的复合物(BRCA1A, B和C),这种结合对于调控BRCA1的功能是至关重要的。
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