Arsenic causes carcinogenicity on human skin through inhibiting the expressions of MGMT, XRCC1 and influencing the genetic stability and the DNA repair function.
砷可能通过抑制砷中毒患者皮肤组织中MGMT、XRCC1等DNA修复基因的表达,影响基因组d NA稳定性和DNA修复功能而导致对皮肤的致癌作用。
BRCA1 protein forms at least three distinct complexes (BRCA1 a, B, and c) with other DNA repair proteins, and these interactions are vital for regulation of BRCA1 function.
BRCA1会和其他DNA损伤蛋白结合形成至少三种不同的复合物(BRCA1A,B和C),这种结合对于调控BRCA1的功能是至关重要的。
BRCA1 forms at least three distinct complexes (BRCA1 a, B, and c) with other DNA repair proteins, and these interactions are vital for the regulation of BRCA1 function.
BRCA1会和其他DNA损伤蛋白结合形成至少三种不同的复合物(BRCA1A,B和C),这种结合对于调控BRCA1的功能是至关重要的。
Cell responses to ionizing radiation are determined by extent and repair capability of DNA damage. Capability of DNA damage repair and character of damage vary as a function of cell cycle.
细胞对电离辐射的反应取决于DNA的损伤程度及细胞对此损伤的修复能力,损伤后修复能力和损伤性质因细胞周期而异。
Cell responses to ionizing radiation are determined by extent and repair capability of DNA damage. Capability of DNA damage repair and character of damage vary as a function of cell cycle.
细胞对电离辐射的反应取决于DNA的损伤程度及细胞对此损伤的修复能力,损伤后修复能力和损伤性质因细胞周期而异。
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