The licking response induced by 4-ap or histamine were also compared.
比较4 - AP与组胺所致小鼠舔体反应的特点。
Objective: To investigate the relationship between 4-aminopyridine (4-ap) -induced licking and itching responses in mice.
目的：探讨4 -氨基吡啶(4 - AP)致小鼠舔体反应与瘙痒的关系。
Nifedipine, a calcium antagonist, and minoxidil, a potassium opener, could inhibit the licking response and prevent the decrease of histamine content in the skin induced by 4-ap.
钙拮抗剂硝苯啶与钾通道开放剂米诺地尔均能抑制4 - AP诱发的小鼠舔体反应，且给4 - AP部位，皮肤组胺含量明显高于对照组。
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