表观基因组(Epigenome)是"DNA序列以外的遗传信息"这个概念的术语.近来,表观基因组的研究得到飞速发展,作为药物研制的新靶标引起了人们的注意.
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贝克的研究着重于表观基因组的变化如何导致癌症。
Beck's work focuses on how changes to the epigenome can lead to cancer.
“这意味着酒精影响了小鼠的表观基因组——控制基因的开启或关闭，”Chong说。
"This means that the alcohol was affecting the epigenome of the mice - controlling whether their genes were switched on or off," says Chong.
李斯特和裴里荣拉博士通过描述最早的两个合理完整的人类表观基因组而验证了这个理论。
Dr Lister and Dr Pelizzola have tested this idea by describing the first two reasonably complete human epigenomes.
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